Welcome to the
Felix Meissner

Department of Systems Immunology & Proteomics

Principal Investigator

Felix Meissner, PhD

Felix Meissner studied biochemistry at the Free University of Berlin and the Scripps Institute in San Diego, USA. He obtained his doctorate at the Max Planck Institute for Infection Biology in Berlin. His postdoctoral work then took him to the Max Planck Institute of Biochemistry in Martinsried and then to the University of California in San Francisco. He then returned to Munich as an independent Research Group Leader for “Experimental System Immunology” at the same Institute. Since 2021 he is heading the Department of "Systems Immunology and Proteomics" at the III in Bonn. He has co-founded Odyssey Therapeutics, which translates discoveries into novel therapeutics.

Our Science

Laboratory focus

The Felix Meissner laboratory develops and applies mass spectrometry-based technologies to identify immune signaling circuits within and between cells that regulate inflammation.  

While inflammation is critical to combat pathogens and maintain tissue homeostasis, its deregulation leads to tissue damage or even inflammatory and autoimmune diseases. The high system complexity of the interplay of multiple cell-types, however, impedes analysis and understanding of immune mechanism that protect us against disease.
We aim to understand how inflammation is regulated on molecular and cellular levels. We address questions of broad relevance to various fields, in which immune reactions play significant roles such as sterile and chronic inflammatory pathologies as well as cancer (see Funding). We employ a unique combination of cellular immunology, biochemistry, mass spectrometry-based proteomics, and systems biology to dissect the complexity of intra- and intercellular immune signaling circuits and reveal functionally relevant regulations. Our disease-agnostic research strategy identifies commonalities and differences in cellular and molecular signaling networks and strategies for targeted interference.

Currently, the Felix Meissner laboratory is located in two places: III Bonn & MPI Martinsried (www.biochem.mpg.de/meissner).

Interested in elucidating the signals and pathways that regulate sterile inflammation?
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