Welcome to the
Anette Christ Laboratory

Translational Immunology Group

Principle Investigator

Anette Christ, PhD

Anette Christ studied biomedical sciences at the University of Tübingen and at the University Aix-Marseille II, France. She obtained her doctorate at the RWTH Aachen University and the University Hospital Maastricht, the Netherlands in 2013. After she moved on to do a Postdoc with Eicke Latz, mainly working in his lab at the University of Massachusetts Medical School in Worcester, USA. She returned to Germany in 2018 to work in the Institute of Innate Immunity at the Medical Faculty in Bonn. Since 2020 she is working as a group leader in Prof. Latz's team. Currently, she is pursuing a part-time M.Sc. in Public Health and Epidemiology.‍

Our Science

Laboratory focus

We aim to better understand the impact of unhealthy Western diets on the long-term health outcome.
One of the overall goals is to detect and analyse the functionality of predictive biomarkers that will help to better understand disease development and progression of chronic lifestyle-associated metabolic diseases. The outcomes likely improve treatment opportunities, but hopefully also support the targeted and efficient implementation of preventive actions at an early stage.
Moreover, we are trying to understand disease development of lifestyle-associated diseases from a societal perspective and to integrate approaches from public health and health services research into our research questions in order to better understand the interactions between diverse environmental factors and molecular signalling pathways.
Hence, our long-term goals are to understand (1) how lifestyle factors influence individual health through molecular changes, (2) what are the long-term consequences on societal health status, and (3) how results could be incorporated into appropriate future prevention formats. In this context, we are particularly interested in using epidemiological methodological tools to measure and describe multiple environmental exposures, particularly during pregnancy and early childhood, in prospective cohort and associate these exposures with molecular omics signatures, but also in clinical interventive approaches to assess whether lifestyle-associated detrimental molecular patterns can be reversed thus improving life quality.